Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF‐kB signaling pathways synergistically

OBJECTIVE: Differentiation‐inducing therapy for tumors is a strategy that aims to induce the differentiation and maturation of cancer stem cells (CSCs). The differentiation‐inducing capacity of arsenic trioxide (ATO) in hepatocellular carcinoma (HCC) and the underlying mechanism were previously unkn...

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Dades bibliogràfiques
Publicat a:Clin Transl Med
Autors principals: Zhang, Xin, Hu, Bo, Sun, Yun‐Fan, Huang, Xiao‐Wu, Cheng, Jian‐Wen, Huang, Ao, Zeng, Hai‐Ying, Qiu, Shuang‐Jian, Cao, Ya, Fan, Jia, Zhou, Jian, Yang, Xin‐Rong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901720/
https://ncbi.nlm.nih.gov/pubmed/33634982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.335
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