Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures

To study the development of the human retina, we use single-cell RNA sequencing (RNA-seq) at key fetal stages and follow the development of the major cell types as well as populations of transitional cells. We also analyze stem cell (hPSC)-derived retinal organoids; although organoids have a very si...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Sridhar, Akshayalakshmi, Hoshino, Akina, Finkbeiner, Connor R., Chitsazan, Alex, Dai, Li, Haugan, Alexandra K., Eschenbacher, Kayla M., Jackson, Dana L., Trapnell, Cole, Bermingham-McDonogh, Olivia, Glass, Ian, Reh, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901645/
https://ncbi.nlm.nih.gov/pubmed/32023475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.007
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