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ADD Force Field for Sugars and Polyols: Predicting the Additivity of Protein–Osmolyte Interaction

[Image: see text] The protein–osmolyte interaction has been shown experimentally to follow an additive construct, where the individual osmolyte–backbone and osmolyte–side-chain interactions contribute to the overall conformational stability of proteins. Here, we computationally reconstruct this addi...

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Detalles Bibliográficos
Publicado en:J Phys Chem B
Autores principales: Arsiccio, Andrea, Ganguly, Pritam, La Cortiglia, Lorenzo, Shea, Joan-Emma, Pisano, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2020
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901642/
https://ncbi.nlm.nih.gov/pubmed/32790371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c05345
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