Stereoselective Synthesis and Structural Confirmation of the Specialized Pro-Resolving Mediator Resolvin E4

[Image: see text] Herein, we report the stereoselective and convergent synthesis of resolvin E4, a newly identified specialized pro-resolving mediator. This synthesis proves the absolute configuration and exact olefin geometry. Key elements of the successful strategy include a highly stereoselective...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Reinertsen, Amalie Føreid, Primdahl, Karoline Gangestad, Shay, Ashley Elizabeth, Serhan, Charles Nicholas, Hansen, Trond Vidar, Aursnes, Marius
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901022/
https://ncbi.nlm.nih.gov/pubmed/33534565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c02913
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