Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish women

Mosaicism in blood varies with age, and cross-sectional studies indicate that for women, skewness of X-chromosomal mosaicism increases with age. This pattern could, however, also be due to less X-inactivation in more recent birth cohorts. Skewed X-chromosome inactivation was here measured longitudin...

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Publicat a:Sci Rep
Autors principals: Mengel-From, Jonas, Lindahl-Jacobsen, Rune, Nygaard, Marianne, Soerensen, Mette, Ørstavik, Karen Helene, Hertz, Jens Michael, Andersen-Ranberg, Karen, Tan, Qihua, Christensen, Kaare
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900237/
https://ncbi.nlm.nih.gov/pubmed/33619309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83702-2
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