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Administration of TGF-ß Inhibitor Mitigates Radiation-induced Fibrosis in a Mouse Model

BACKGROUND: Radiation-induced fibrosis is a long-term adverse effect of external beam radiation therapy for cancer treatment that can cause pain, loss of function, and decreased quality of life. Transforming growth factor beta (TGF-β) is believed to be critical to the development of radiation-induce...

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Detalhes bibliográficos
Publicado no:Clin Orthop Relat Res
Main Authors: Gans, Itai, El Abiad, Jad M., James, Aaron W., Levin, Adam S., Morris, Carol D.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899598/
https://ncbi.nlm.nih.gov/pubmed/33252888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CORR.0000000000001286
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