Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

Rationally designed protein subunit vaccines are being developed for a variety of viruses including influenza, RSV, SARS-CoV-2 and HIV. These vaccines are based on stabilized versions of the primary targets of neutralizing antibodies on the viral surface, namely viral fusion glycoproteins. While the...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Turner, Hannah L., Andrabi, Raiees, Cottrell, Christopher A., Richey, Sara T., Song, Ge, Callaghan, Sean, Anzanello, Fabio, Moyer, Tyson J., Abraham, Wuhbet, Melo, Mariane, Silva, Murillo, Scaringi, Nicole, Rakasz, Eva G., Sattentau, Quentin, Irvine, Darrell J., Burton, Dennis R., Ward, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899455/
https://ncbi.nlm.nih.gov/pubmed/33619491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.16.431310
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