A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice

Juvenile social isolation reduces sociability in adulthood, but the neural circuit mechanisms are poorly understood. We found that, in male mice, 2 weeks of social isolation immediately following weaning leads to a failure to activate medial prefrontal cortex (mPFC) neurons projecting to the posteri...

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Udgivet i:Nat Neurosci
Main Authors: Yamamuro, Kazuhiko, Bicks, Lucy K., Leventhal, Michael B., Kato, Daisuke, Im, Susanna, Flanigan, Meghan E., Garkun, Yury, Norman, Kevin J., Caro, Keaven, Sadahiro, Masato, Kullander, Klas, Akbarian, Schahram, Russo, Scott J., Morishita, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898783/
https://ncbi.nlm.nih.gov/pubmed/32868932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-0695-6
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