Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments

BACKGROUND: The mu-opioid agonist methadone is administered orally and used in opioid detoxification and in the treatment of moderate-to-severe pain. Acute oral methadone–use and –abuse have been associated with inflammatory and toxic central nervous system (CNS) damage in some cases and cognitive d...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Repple, Jonathan, Haessner, Svea, Johnen, Andreas, Landmeyer, Nils C., Schulte-Mecklenbeck, Andreas, Pawlitzki, Marc, Wiendl, Heinz, Meyer zu Hörste, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898738/
https://ncbi.nlm.nih.gov/pubmed/33618681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-021-02108-9
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