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Gut Microbiota and Related Metabolites Were Disturbed in Ulcerative Colitis and Partly Restored After Mesalamine Treatment

Mesalamine has been well used in the improvement of ulcerative colitis (UC) in clinics, however, the underlying mechanisms were not well illustrated. To explore its efficacy from the perspective of gut microbiota and related metabolites, we employed 16S rRNA sequencing and metabolomics approaches in...

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Vydáno v:Front Pharmacol
Hlavní autoři: Dai, Liang, Tang, Yingjue, Zhou, Wenjun, Dang, Yanqi, Sun, Qiaoli, Tang, Zhipeng, Zhu, Mingzhe, Ji, Guang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898679/
https://ncbi.nlm.nih.gov/pubmed/33628183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.620724
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