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Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family

The human glucose transporters GLUT1 and GLUT3 have a central role in glucose uptake as canonical members of the Sugar Porter (SP) family. GLUT1 and GLUT3 share a fully conserved substrate-binding site with identical substrate coordination, but differ significantly in transport affinity in line with...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Custódio, Tânia Filipa, Paulsen, Peter Aasted, Frain, Kelly May, Pedersen, Bjørn Panyella
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898563/
https://ncbi.nlm.nih.gov/pubmed/33536238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000858
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