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The ubiquitin ligase RNF8 regulates Rho GTPases and promotes cytoskeletal changes and motility in triple‐negative breast cancer cells

The ubiquitin ligase RNF8 is known to induce epithelial‐to‐mesenchymal (EMT) transition and metastasis in triple‐negative breast cancer (TNBC). Besides EMT, Rho GTPases have been shown as key regulators in metastasis. In this study, we investigated the role of RNF8 in regulating Rho GTPases and cell...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Pereira De Carvalho, Bruno, Chern, Yi‐Jye, He, Jiabei, Chan, Chia‐Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898409/
https://ncbi.nlm.nih.gov/pubmed/33205415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13999
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