Molecular and biochemical characterization of the bicarbonate-sensing soluble adenylyl cyclase from a bony fish, the rainbow trout Oncorhynchus mykiss

Soluble adenylyl cyclase (sAC) is a [Formula: see text]-stimulated enzyme that produces the ubiquitous signalling molecule cAMP, and deemed an evolutionarily conserved acid–base sensor. However, its presence is not yet confirmed in bony fishes, the most abundant and diverse of vertebrates. Here, we...

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Published in:Interface Focus
Main Authors: Salmerón, Cristina, Harter, Till S., Kwan, Garfield T., Roa, Jinae N., Blair, Salvatore D., Rummer, Jodie L., Shiels, Holly A., Goss, Greg G., Wilson, Rod W., Tresguerres, Martin
Format: Artigo
Language:Inglês
Published: The Royal Society 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898143/
https://ncbi.nlm.nih.gov/pubmed/33633829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2020.0026
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