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Proposal of selective wedge instillation of pulmonary surfactant for COVID-19 pneumonia based on computational fluid dynamics simulation

BACKGROUND: The most important target cell of SARS-CoV-2 is Type II pneumocyte which produces and secretes pulmonary surfactant (PS) that prevents alveolar collapse. PS instillation therapy is dramatically effective for infant respiratory distress syndrome but has been clinically ineffective for ARD...

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Bibliografiske detaljer
Udgivet i:BMC Pulm Med
Main Authors: Kitaoka, Hiroko, Kobayashi, Hisato, Takimoto, Takayuki, Kijima, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897887/
https://ncbi.nlm.nih.gov/pubmed/33618696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-021-01435-4
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