A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae

The construction of microbial cell factories for sustainable production of chemicals and pharmaceuticals requires extensive genome engineering. Using Saccharomyces cerevisiae, this study proposes synthetic neochromosomes as orthogonal expression platforms for rewiring native cellular processes and i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Postma, Eline D, Dashko, Sofia, van Breemen, Lars, Taylor Parkins, Shannara K, van den Broek, Marcel, Daran, Jean-Marc, Daran-Lapujade, Pascale
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2021
Pynciau:
Synthetic Biology and Bioengineering
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897487/
https://ncbi.nlm.nih.gov/pubmed/33423048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1167
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