A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae

The construction of microbial cell factories for sustainable production of chemicals and pharmaceuticals requires extensive genome engineering. Using Saccharomyces cerevisiae, this study proposes synthetic neochromosomes as orthogonal expression platforms for rewiring native cellular processes and i...

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Publicado en:Nucleic Acids Res
Autores principales: Postma, Eline D, Dashko, Sofia, van Breemen, Lars, Taylor Parkins, Shannara K, van den Broek, Marcel, Daran, Jean-Marc, Daran-Lapujade, Pascale
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897487/
https://ncbi.nlm.nih.gov/pubmed/33423048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1167
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