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A Reporter Mouse for In Vivo Detection of DNA Damage in Embryonic Germ Cells

Maintaining genome integrity in the germline is essential for survival and propagation of a species. In both mouse and human, germ cells originate during fetal development and are hypersensitive to both endogenous and exogenous DNA damaging agents. Currently, mechanistic understanding of how primord...

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Bibliografiske detaljer
Udgivet i:Genesis
Main Authors: Bloom, Jordana C., Schimenti, John C.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897368/
https://ncbi.nlm.nih.gov/pubmed/32343484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23368
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