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Activity labeling in vivo using CaMPARI2 reveals intrinsic and synaptic differences between neurons with high and low firing rate set points

Neocortical pyramidal neurons regulate firing around a stable mean firing rate (FR) that can differ by orders of magnitude between neurons, but the factors that determine where individual neurons sit within this broad FR distribution are not understood. To access low and high FR neurons for ex vivo...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Trojanowski, Nicholas F., Bottorff, Juliet, Turrigiano, Gina G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897300/
https://ncbi.nlm.nih.gov/pubmed/33333001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2020.11.027
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