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Transport mechanisms of SARS-CoV-E viroporin in calcium solutions: Lipid-dependent Anomalous Mole Fraction Effect and regulation of pore conductance

The envelope protein E of the SARS-CoV coronavirus is an archetype of viroporin. It is a small hydrophobic protein displaying ion channel activity that has proven highly relevant in virus-host interaction and virulence. Ion transport through E channel was shown to alter Ca(2+) homeostasis in the cel...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Biomembr
Main Authors: Verdiá-Báguena, Carmina, Aguilella, Vicente M., Queralt-Martín, María, Alcaraz, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896491/
https://ncbi.nlm.nih.gov/pubmed/33621516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2021.183590
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