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One-dimensional diffusion of TrpR along DNA enhances its affinity for the operator by chemical ratchet mechanism

Several DNA-binding proteins show the affinities for their specific DNA sites that positively depend on the length of DNA harboring the sites, i. e. antenna effect. DNA looping can cause the effect for proteins with two or more DNA binding sites, i. e. the looping mechanism. One-dimensional diffusio...

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Publicado en:Sci Rep
Main Authors: Kinebuchi, Takashi, Shimamoto, Nobuo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896080/
https://ncbi.nlm.nih.gov/pubmed/33608564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83156-6
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