Widespread signatures of natural selection across human complex traits and functional genomic categories

Understanding how natural selection has shaped genetic architecture of complex traits is of importance in medical and evolutionary genetics. Bayesian methods have been developed using individual-level GWAS data to estimate multiple genetic architecture parameters including selection signature. Here,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zeng, Jian, Xue, Angli, Jiang, Longda, Lloyd-Jones, Luke R., Wu, Yang, Wang, Huanwei, Zheng, Zhili, Yengo, Loic, Kemper, Kathryn E., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M., Yang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896067/
https://ncbi.nlm.nih.gov/pubmed/33608517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21446-3
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