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Herpes simplex virus-1 KOS-63 strain is virulent and causes titer-dependent corneal nerve damage and keratitis

To investigate the acute clinical, immunological, and corneal nerve changes following corneal HSV-1 KOS-63 strain inoculation. Corneas of C57BL/6 mice were inoculated with either low dose (Ld) or high dose (Hd) HSV-1 KOS-63 or culture medium. Clinical evaluation was conducted up to 7 days post inocu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moein, Hamid-Reza, Sendra, Victor G., Jamali, Arsia, Kheirkhah, Ahmad, Harris, Deshea L., Hamrah, Pedram
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895966/
https://ncbi.nlm.nih.gov/pubmed/33608598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83412-9
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