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Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen

The receptor for Colony Stimulating Factor 1 (CSF1), c-fms, is highly expressed on mature osteoclasts suggesting a role for this cytokine in regulating the function of these cells. Consistent with this idea, in vitro studies have documented a variety of effects of CSF1 in mature osteoclasts. To bett...

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מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Zhu, Meiling, Sun, Ben-hua, Nevius, Erin, Kaplan, Jared, Pereira, João, Insogna, Karl
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895546/
https://ncbi.nlm.nih.gov/pubmed/33607650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247199
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