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Loss of cortical control over the descending pain modulatory system determines the development of the neuropathic pain state in rats

The loss of descending inhibitory control is thought critical to the development of chronic pain but what causes this loss in function is not well understood. We have investigated the dynamic contribution of prelimbic cortical neuronal projections to the periaqueductal grey (PrL-P) to the developmen...

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Vydáno v:eLife
Hlavní autoři: Drake, Robert AR, Steel, Kenneth A, Apps, Richard, Lumb, Bridget M, Pickering, Anthony E
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895525/
https://ncbi.nlm.nih.gov/pubmed/33555256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65156
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