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Mapping parameter spaces of biological switches

Since the seminal 1961 paper of Monod and Jacob, mathematical models of biomolecular circuits have guided our understanding of cell regulation. Model-based exploration of the functional capabilities of any given circuit requires systematic mapping of multidimensional spaces of model parameters. Desp...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Diegmiller, Rocky, Zhang, Lun, Gameiro, Marcio, Barr, Justinn, Imran Alsous, Jasmin, Schedl, Paul, Shvartsman, Stanislav Y., Mischaikow, Konstantin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895388/
https://ncbi.nlm.nih.gov/pubmed/33556054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008711
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