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A durable protective immune response to wild-type measles virus infection of macaques is due to viral replication and spread in lymphoid tissues

Infection with wild-type (WT) measles virus (MeV) is an important cause of childhood mortality that leads to lifelong protective immunity in survivors. WT MeV and the live-attenuated MeV used in the measles vaccine (LAMV) are antigenically similar, but the determinants of attenuation are unknown, an...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Lin, Wen-Hsuan W., Moran, Eileen, Adams, Robert J., Sievers, Robert E., Hauer, Debra, Godin, Steven, Griffin, Diane E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895323/
https://ncbi.nlm.nih.gov/pubmed/32238577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax7799
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