A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent

Effective intervention strategies are urgently needed to control the COVID-19 pandemic. Human angiotensin-converting enzyme 2 (ACE2) is a membrane-bound carboxypeptidase that forms a dimer and serves as the cellular receptor for SARS‑CoV‑2. ACE2 is also a key negative regulator of the renin-angioten...

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Publicado no:Nat Struct Mol Biol
Main Authors: Xiao, Tianshu, Lu, Jianming, Zhang, Jun, Johnson, Rebecca I., McKay, Lindsay G.A., Storm, Nadia, Lavine, Christy L., Peng, Hanqin, Cai, Yongfei, Rits-Volloch, Sophia, Lu, Shen, Quinlan, Brian D., Farzan, Michael, Seaman, Michael S., Griffiths, Anthony, Chen, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895301/
https://ncbi.nlm.nih.gov/pubmed/33432247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00549-3
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