Spatiotemporal relationship between subthreshold amyloid accumulation and aerobic glycolysis in the human brain

In Alzheimer’s disease, brain amyloid deposition has a distinct topography that correlates with aerobic glycolysis (AG), i.e., the use of glucose in the brain beyond that predicted by oxygen consumption. The causes for this relationship remain unclear but might provide critical insight into how and...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Goyal, Manu S., Gordon, Brian A., Couture, Lars E., Flores, Shaney, Xiong, Chengjie, Morris, John C., Raichle, Marcus E., Benzinger, Tammie L-S., Vlassenko, Andrei G.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894981/
https://ncbi.nlm.nih.gov/pubmed/33011615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.08.019
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