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Targeting B cells for inflammatory bowel disease treatment: back to the future

B cells are critical to immune homeostasis at mucosal surfaces including those of the gastrointestinal tract. B cell-related abnormalities, comprising of a lympho-plasmacytic infiltrate, as well as anti-microbial antibodies, are well reported in patients with inflammatory bowel disease (IBD). Howeve...

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Detalhes bibliográficos
Publicado no:Curr Opin Pharmacol
Main Authors: Castro-Dopico, Tomas, Colombel, Jean-Frederic, Mehandru, Saurabh
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894973/
https://ncbi.nlm.nih.gov/pubmed/33166872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2020.10.002
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