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AG-1024 Sensitizes Sorafenib-Resistant Hepatocellular Carcinoma Cells to Sorafenib via Enhancing G1/S Arrest

PURPOSE: The frequency in resistance to sorafenib accounts for the grim prognosis of advanced hepatocellular carcinoma (HCC). In the present study, we explore the anti-cancer efficacy of co-administration of sub-toxic AG-1024 with sorafenib in HCC cells to enhance the sensitivity of these cells to s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Onco Targets Ther
Prif Awduron: Zhou, Wei, Lou, Weiyang, Chen, Junru, Ding, Bisha, Chen, Binjie, Xie, Haiyang, Zhou, Lin, Zheng, Shusen, Jiang, Donghai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894871/
https://ncbi.nlm.nih.gov/pubmed/33623392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S289324
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