Sex, Permanent Drug Discontinuation and Study Retention in Clinical Trials: Insights from the TIMI trials

BACKGROUND: Women are underrepresented across cardiovascular clinical trials. Whether women are more likely than men to prematurely discontinue study drug or withdraw consent once enrolled in a clinical trial is unknown. METHODS: Eleven phase 3/4 TIMI trials were included [135,879 men and 51,812 wom...

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Publicat a:Circulation
Autors principals: Lau, Emily S., Braunwald, Eugene, Morrow, David A., Giugliano, Robert P., Antman, Elliott M., Gibson, C. Michael, Scirica, Benjamin M., Bohula, Erin A., Wiviott, Stephen D., Bhatt, Deepak L., Bonaca, Marc P., Cannon, Christopher P., Im, KyungAh, Guo, Jianping, Sabatine, Marc S., O’Donoghue, Michelle L.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894618/
https://ncbi.nlm.nih.gov/pubmed/33587654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.052339
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