Sex, Permanent Drug Discontinuation and Study Retention in Clinical Trials: Insights from the TIMI trials

BACKGROUND: Women are underrepresented across cardiovascular clinical trials. Whether women are more likely than men to prematurely discontinue study drug or withdraw consent once enrolled in a clinical trial is unknown. METHODS: Eleven phase 3/4 TIMI trials were included [135,879 men and 51,812 wom...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Lau, Emily S., Braunwald, Eugene, Morrow, David A., Giugliano, Robert P., Antman, Elliott M., Gibson, C. Michael, Scirica, Benjamin M., Bohula, Erin A., Wiviott, Stephen D., Bhatt, Deepak L., Bonaca, Marc P., Cannon, Christopher P., Im, KyungAh, Guo, Jianping, Sabatine, Marc S., O’Donoghue, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894618/
https://ncbi.nlm.nih.gov/pubmed/33587654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.052339
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