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A High‐Yielding Synthesis of EIDD‐2801 from Uridine
A simple reordering of the reaction sequence allowed the improved synthesis of EIDD‐2801, an antiviral drug with promising activity against the SARS‐CoV‐2 virus, starting from uridine. Compared to the original route, the yield was enhanced from 17 % to 61 %, and fewer isolation/purification steps we...
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| Yayımlandı: | European J Org Chem |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7894511/ https://ncbi.nlm.nih.gov/pubmed/33664631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.202001340 |
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