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A High‐Yielding Synthesis of EIDD‐2801 from Uridine
A simple reordering of the reaction sequence allowed the improved synthesis of EIDD‐2801, an antiviral drug with promising activity against the SARS‐CoV‐2 virus, starting from uridine. Compared to the original route, the yield was enhanced from 17 % to 61 %, and fewer isolation/purification steps we...
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| 出版年: | European J Org Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7894511/ https://ncbi.nlm.nih.gov/pubmed/33664631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.202001340 |
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