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Challenges of Using Expansion Microscopy for Super‐resolved Imaging of Cellular Organelles

Expansion microscopy (ExM) has been successfully used to improve the spatial resolution when imaging tissues by optical microscopy. In ExM, proteins of a fixed sample are crosslinked to a swellable acrylamide gel, which expands when incubated in water. Therefore, ExM allows enlarged subcellular stru...

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Bibliografiske detaljer
Udgivet i:Chembiochem
Main Authors: Büttner, Maximilian, Lagerholm, Christoffer B., Waithe, Dominic, Galiani, Silvia, Schliebs, Wolfgang, Erdmann, Ralf, Eggeling, Christian, Reglinski, Katharina
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894168/
https://ncbi.nlm.nih.gov/pubmed/33049107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000571
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