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Trastuzumab immunogenicity development in patients’ sera and in laboratory animals
BACKGROUND: Immunogenicity is a major challenge in drug development and patient care. Clinicians and regulators are familiar with immunogenicity concerns of monoclonal antibody (mAb) therapeutics, growth factors and enzyme replacements. Although most small therapeutic molecules are unlikely to trigg...
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| 出版年: | BMC Immunol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7893875/ https://ncbi.nlm.nih.gov/pubmed/33607941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-021-00405-z |
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