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Trastuzumab immunogenicity development in patients’ sera and in laboratory animals

BACKGROUND: Immunogenicity is a major challenge in drug development and patient care. Clinicians and regulators are familiar with immunogenicity concerns of monoclonal antibody (mAb) therapeutics, growth factors and enzyme replacements. Although most small therapeutic molecules are unlikely to trigg...

詳細記述

保存先:
書誌詳細
出版年:BMC Immunol
主要な著者: Kilany, Lobna Abdel Aziz, Gaber, Ayman Abdel Samie, Aboulwafa, Mohammad Mabrouk, Zedan, Hamdallah Hafez
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893875/
https://ncbi.nlm.nih.gov/pubmed/33607941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-021-00405-z
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