Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease with a poor cure rate for relapsed/resistant patients. Due to the lack of T-cell restricted targetable antigens, effective immune-therapeutics are not presently available and the treatment of chemo-refractory T-ALL is s...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Caracciolo, Daniele, Riillo, Caterina, Ballerini, Andrea, Gaipa, Giuseppe, Lhermitte, Ludovic, Rossi, Marco, Botta, Cirino, Duroyon, Eugénie, Grillone, Katia, Gallo Cantafio, Maria Eugenia, Buracchi, Chiara, Alampi, Greta, Gulino, Alessandro, Belmonte, Beatrice, Conforti, Francesco, Golino, Gaetanina, Juli, Giada, Altomare, Emanuela, Polerà, Nicoletta, Scionti, Francesca, Arbitrio, Mariamena, Iannone, Michelangelo, Martino, Massimo, Correale, Pierpaolo, Talarico, Gabriella, Ghelli Luserna di Rorà, Andrea, Ferrari, Anna, Concolino, Daniela, Sestito, Simona, Pensabene, Licia, Giordano, Antonio, Hildinger, Markus, Di Martino, Maria Teresa, Martinelli, Giovanni, Tripodo, Claudio, Asnafi, Vahid, Biondi, Andrea, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Basic Tumor Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893666/
https://ncbi.nlm.nih.gov/pubmed/33597219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002026
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