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Recent Advances in Metabolic Engineering, Protein Engineering, and Transcriptome-Guided Insights Toward Synthetic Production of Taxol

The diterpenoid paclitaxel (Taxol(®)) is a blockbuster anticancer agent that was originally isolated from the Pacific yew (Taxus brevifolia) five decades ago. Despite the wealth of information gained over the years on Taxol research, there still remains supply issues to meet increasing clinical dema...

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Publicat a:Front Bioeng Biotechnol
Autors principals: Mutanda, Ishmael, Li, Jianhua, Xu, Fanglin, Wang, Yong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892896/
https://ncbi.nlm.nih.gov/pubmed/33614616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.632269
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