Bronchoalveolar Lavage Fluid Reflects a T(H)1-CD21(low) B-Cell Interaction in CVID-Related Interstitial Lung Disease

BACKGROUND: About 20% of patients with common variable immunodeficiency (CVID) suffer from interstitial lung disease (ILD) as part of a systemic immune dysregulation. Current understanding suggests a role of B cells in the pathogenesis based on histology and increased levels of BAFF and IgM associat...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Friedmann, David, Unger, Susanne, Keller, Baerbel, Rakhmanov, Mirzokhid, Goldacker, Sigune, Zissel, Gernot, Frye, Björn C., Schupp, Jonas C., Prasse, Antje, Warnatz, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892466/
https://ncbi.nlm.nih.gov/pubmed/33613543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.616832
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