Age and Origin of the Founder Antithrombin Budapest 3 (p.Leu131Phe) Mutation; Its High Prevalence in the Roma Population and Its Association With Cardiovascular Diseases

Background: Antithrombin (AT) is one of the most important regulator of hemostasis. AT Budapest 3 (ATBp3) is a prevalent type II heparin-binding site (IIHBS) deficiency due to founder effect. Thrombosis is a complex disease including arterial (ATE) and venous thrombotic events (VTE) and the Roma pop...

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發表在:Front Cardiovasc Med
Main Authors: Bereczky, Zsuzsanna, Gindele, Réka, Fiatal, Szilvia, Speker, Marianna, Miklós, Tünde, Balogh, László, Mezei, Zoltán, Szabó, Zsuzsanna, Ádány, Róza
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2021
主題:
Cardiovascular Medicine
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892435/
https://ncbi.nlm.nih.gov/pubmed/33614741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.617711
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