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A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance
Current evidence indicates that resistance to the tyrosine kinase-type cell surface receptor (HER2)-targeted therapies is frequently associated with HER3 and active signaling via HER2-HER3 dimers, particularly in the context of breast cancer. Thus, understanding the response to HER2-HER3 signaling a...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7892347/ https://ncbi.nlm.nih.gov/pubmed/33420373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01604-5 |
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