Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions

Bone metastasis remains a major cause of mortality and morbidity in breast cancer. Therefore, there is an urgent need to better select high-risk patients in order to adapt patient’s treatment and prevent bone recurrence. Here, we found that integrin alpha5 (ITGA5) was highly expressed in bone metast...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Pantano, Francesco, Croset, Martine, Driouch, Keltouma, Bednarz-Knoll, Natalia, Iuliani, Michele, Ribelli, Giulia, Bonnelye, Edith, Wikman, Harriet, Geraci, Sandra, Bonin, Florian, Simonetti, Sonia, Vincenzi, Bruno, Hong, Saw See, Sousa, Sofia, Pantel, Klaus, Tonini, Giuseppe, Santini, Daniele, Clézardin, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892344/
https://ncbi.nlm.nih.gov/pubmed/33420367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01603-6
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