PAI-1 derived from cancer-associated fibroblasts in esophageal squamous cell carcinoma promotes the invasion of cancer cells and the migration of macrophages

Cancer-associated fibroblasts (CAFs) contribute to the progression of various cancers. Previously, we reported the significance of CAFs in esophageal squamous cell carcinoma (ESCC); however, the functions of CAFs in the ESCC microenvironment remain unknown. To investigate CAFs’ function, we establis...

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Publicat a:Lab Invest
Autors principals: Sakamoto, Hiroki, Koma, Yu-ichiro, Higashino, Nobuhide, Kodama, Takayuki, Tanigawa, Kohei, Shimizu, Masaki, Fujikawa, Masataka, Nishio, Mari, Shigeoka, Manabu, Kakeji, Yoshihiro, Yokozaki, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group US 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892342/
https://ncbi.nlm.nih.gov/pubmed/33311557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-020-00512-2
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