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Inhibition of CXCR2 alleviates the development of abdominal aortic aneurysm in Apo E(-/-) mice
PURPOSE: To investigate the relationship between atherosclerotic abdominal aortic aneurysm (AAA) and CXC chemokine receptor type 2 (CXCR2). METHODS: Mouse AAA model was established by embedding angiotensin-II pump (1000 ng/kg/min) in ApoE(-/-) mice. Mice were received SB225002, a selective CXCR2 ant...
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| Publicado no: | Acta Cir Bras |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em
Cirurgia
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7892195/ https://ncbi.nlm.nih.gov/pubmed/33605308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/ACB360105 |
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