Quantification of brain proton longitudinal relaxation (T(1)) in lithium‐treated and lithium‐naïve patients with bipolar disorder in comparison to healthy controls

BACKGROUND: Proton longitudinal relaxation (T(1)) is a quantitative MRI‐derived tissue parameter sensitive to myelin, macromolecular, iron and water content. There is some evidence to suggest that cortical T(1) is elevated in bipolar disorder and that lithium administration reduces cortical T(1). Ho...

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Detalhes bibliográficos
Publicado no:Bipolar Disord
Main Authors: Necus, Joe, Smith, Fiona Elizabeth, Thelwall, Peter Edward, Flowers, Carly Jay, Sinha, Nishant, Taylor, Peter Neal, Blamire, Andrew Matthew, Wang, Yujiang, Cousins, David Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891392/
https://ncbi.nlm.nih.gov/pubmed/31755171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bdi.12878
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