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Rationale and Design of the Genotype-Blinded Trial of Torasemide for the Treatment of Hypertension (BHF UMOD)

BACKGROUND: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near the uromodulin gene (UMOD) affecting uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb (TAL) of the loop of Henle and its effect...

詳細記述

保存先:
書誌詳細
出版年:Am J Hypertens
主要な著者: McCallum, Linsay, Brooksbank, Katriona, McConnachie, Alex, Aman, Alisha, Lip, Stefanie, Dawson, Jesse, MacIntyre, Iain M, MacDonald, Thomas M, Webb, David J, Padmanabhan, Sandosh
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891239/
https://ncbi.nlm.nih.gov/pubmed/33084880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpaa166
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