Rationale and Design of the Genotype-Blinded Trial of Torasemide for the Treatment of Hypertension (BHF UMOD)

BACKGROUND: Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near the uromodulin gene (UMOD) affecting uromodulin excretion and blood pressure (BP). Uromodulin is almost exclusively expressed in the thick ascending limb (TAL) of the loop of Henle and its effect...

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Bibliografski detalji
Izdano u:Am J Hypertens
Glavni autori: McCallum, Linsay, Brooksbank, Katriona, McConnachie, Alex, Aman, Alisha, Lip, Stefanie, Dawson, Jesse, MacIntyre, Iain M, MacDonald, Thomas M, Webb, David J, Padmanabhan, Sandosh
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Original Contributions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891239/
https://ncbi.nlm.nih.gov/pubmed/33084880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpaa166
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