The Clinical Significance of Promoter Methylation of Fluoropyrimidine Metabolizing and Cyclooxygenase Genes in Colorectal Cancer

AIMS: This study investigated the impact of promoter methylation of flouropyrimidine (FP) metabolizing and cyclooxygenase 2 (COX2) genes on their mRNA expression and on the clinical outcome of colorectal cancer (CRC) patients. METHODS: Methylation specific-PCR and real time-PCR of thymidylate syntha...

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Detalhes bibliográficos
Publicado no:Epigenet Insights
Main Authors: Fouad, Mariam Ahmed, Salem, Salem Eid, Hussien, Marwa M., Badr, Doaa Mohamed, Zekri, Abdelrahman N., Hafez, Hafez Farouk, Shouman, Samia A.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890744/
https://ncbi.nlm.nih.gov/pubmed/33644686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2516865720986231
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