Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain

BACKGROUND: Paclitaxel is a widely prescribed chemotherapy drug for treating solid tumors. However, paclitaxel-induced peripheral neuropathy (PIPN) is a common adverse effect during paclitaxel treatment, which results in sensory abnormalities and neuropathic pain among patients. Unfortunately, the m...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Li, Yuanyuan, Yin, Chengyu, Liu, Boyu, Nie, Huimin, Wang, Jie, Zeng, Danyi, Chen, Ruixiang, He, Xiaofen, Fang, Junfan, Du, Junying, Liang, Yi, Jiang, Yongliang, Fang, Jianqiao, Liu, Boyi
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890637/
https://ncbi.nlm.nih.gov/pubmed/33602238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02098-y
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