Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers

BACKGROUND: Natural products are a valuable source of biologically active compounds that have applications in medicine and agriculture. One disadvantage with natural products is the slow, time-consuming strain improvement regimes that are necessary to ensure sufficient quantities of target compounds...

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Bibliografiske detaljer
Udgivet i:Microb Cell Fact
Main Authors: Pikl, Špela, Rincón, Andrés Felipe Carrillo, Slemc, Lucija, Goranovič, Dušan, Avbelj, Martina, Gjuračić, Krešimir, Sucipto, Hilda, Stare, Katja, Baebler, Špela, Šala, Martin, Guo, Meijin, Luzhetskyy, Andriy, Petković, Hrvoje, Magdevska, Vasilka
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890619/
https://ncbi.nlm.nih.gov/pubmed/33596911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01522-5
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