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Targeting Toll-like receptor-4 (TLR4) – emerging therapeutic target for persistent pain states

Toll-like receptors (TLRs) are a family of pattern-recognition receptors that initiate signaling in innate and adaptive immune pathways. The highly conserved family of transmembrane proteins are comprised of an extracellular domain that recognizes exogenous and endogenous danger molecules and an ect...

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Détails bibliographiques
Publié dans:Pain
Auteurs principaux: Bruno, Kelly, Woller, Sarah A., Miller, Yury I., Yaksh, Tony L., Wallace, Mark, Beaton, Graham, Chakravarthy, Krishnan
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890571/
https://ncbi.nlm.nih.gov/pubmed/29889119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001306
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