HELIGMOSOMOIDES BAKERI INFECTION DECREASES SMAD7 EXPRESSION IN INTESTINAL CD4+ T CELLS WHICH ALLOWS TGFβ TO INDUCE IL10-PRODUCING REGULATORY T CELLS THAT BLOCK COLITIS

Helminthic infections modulate host immunity and may protect their hosts from developing immunological diseases like inflammatory bowel disease (IBD). Induction of regulatory T cells (Tregs) may be an important part of this protective process. Heligmosomoides polygyrus bakeri (Hpb) infection also pr...

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Publicado en:J Immunol
Autores principales: Hang, Long, Kumar, Sangeeta, Blum, Arthur M, Urban, Joseph F, Fantini, Massimo C, Weinstock, Joel V
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890536/
https://ncbi.nlm.nih.gov/pubmed/30850474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801392
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