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HELIGMOSOMOIDES BAKERI INFECTION DECREASES SMAD7 EXPRESSION IN INTESTINAL CD4+ T CELLS WHICH ALLOWS TGFβ TO INDUCE IL10-PRODUCING REGULATORY T CELLS THAT BLOCK COLITIS
Helminthic infections modulate host immunity and may protect their hosts from developing immunological diseases like inflammatory bowel disease (IBD). Induction of regulatory T cells (Tregs) may be an important part of this protective process. Heligmosomoides polygyrus bakeri (Hpb) infection also pr...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7890536/ https://ncbi.nlm.nih.gov/pubmed/30850474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801392 |
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