Single‐cell RNA sequencing and lipidomics reveal cell and lipid dynamics of fat infiltration in skeletal muscle

BACKGROUND: Ageing is accompanied by sarcopenia and intramuscular fat (IMAT) infiltration. In skeletal muscle, fat infiltration is a common feature in several myopathies and is associated with muscular dysfunction and insulin resistance. However, the cellular origin and lipidomic and transcriptomic...

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Publicado en:J Cachexia Sarcopenia Muscle
Main Authors: Xu, Ziye, You, Wenjing, Chen, Wentao, Zhou, Yanbing, Nong, Qiuyun, Valencak, Teresa G., Wang, Yizhen, Shan, Tizhong
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890272/
https://ncbi.nlm.nih.gov/pubmed/33244879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12643
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