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In silico designing of putative peptides for targeting pathological protein Htt in Huntington's disease

Huntington's disease is a neurodegenerative disease caused by CAG repeat in the first exon of HTT (Huntingtin) gene, leading to abnormal form of Htt protein containing enlarged polyglutamine strands of variable length that stick together to form aggregates and is toxic to brain causing brain da...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Kohli, Harleen, Kumar, Pravir, Ambasta, Rashmi K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890153/
https://ncbi.nlm.nih.gov/pubmed/33659724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06088
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